Which two syrups are used as vehicles for drugs stable in acidic medium?

Which two syrups are used as vehicles for drugs stable in acidic medium?

• A. Strawberry and Raspberry
• B. Cherry and Orange
• C. Grape and Lemon
• D. Vanilla and Mint

Answer: (B)

When a drug is stable in acidic conditions, using a vehicle that provides and maintains an acidic environment helps keep the drug dissolved and protected from degradation. Cherry and orange syrups are commonly used for this purpose because they have a mildly acidic pH due to natural fruit acids and added acids, which supports stability of acid-stable drugs while also masking taste and providing good palatability. Other syrups may be neutral or have varying acidity that doesn’t reliably maintain the desired acidic milieu, so they’re not as generally suitable as vehicles for these drugs.

When a drug is stable in acidic conditions, using a vehicle that provides and maintains an acidic environment helps keep the drug dissolved and protected from degradation. Cherry and orange syrups are commonly used for this purpose because they have a mildly acidic pH due to natural fruit acids and added acids, which supports stability of acid-stable drugs while also masking taste and providing good palatability. Other syrups may be neutral or have varying acidity that doesn’t reliably maintain the desired acidic milieu, so they’re not as generally suitable as vehicles for these drugs.