Which term describes the migration of the droplets of the internal phase to the top or bottom of an emulsion?

Study for the Pharmaceutics II Exam 2 Concepts Test with flashcards and multiple choice questions. Each question has hints and explanations. Prepare effectively for your exam!

Multiple Choice

Which term describes the migration of the droplets of the internal phase to the top or bottom of an emulsion?

Explanation:
Creaming is the movement of droplets of the dispersed phase up or down within an emulsion due to a density difference with the continuous phase. If the internal phase is less dense than the external phase, droplets rise to the top, forming a cream layer; if it’s denser, they sink. This is a reversible, physical separation driven by gravity and buoyancy, and it can be slowed or reversed by making droplets smaller, increasing the viscosity of the continuous phase, or adjusting densities. Flocculation involves droplets sticking together but staying separate as individual droplets, so there isn’t a net upward or downward migration. Coalescence is when droplets fuse to form larger droplets, leading to instability that worsens over time. Breaking describes a more severe failure where the emulsion completely separates into distinct phases.

Creaming is the movement of droplets of the dispersed phase up or down within an emulsion due to a density difference with the continuous phase. If the internal phase is less dense than the external phase, droplets rise to the top, forming a cream layer; if it’s denser, they sink. This is a reversible, physical separation driven by gravity and buoyancy, and it can be slowed or reversed by making droplets smaller, increasing the viscosity of the continuous phase, or adjusting densities.

Flocculation involves droplets sticking together but staying separate as individual droplets, so there isn’t a net upward or downward migration. Coalescence is when droplets fuse to form larger droplets, leading to instability that worsens over time. Breaking describes a more severe failure where the emulsion completely separates into distinct phases.

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