Which sterilizing filter is used for small volume solutions?

Which sterilizing filter is used for small volume solutions?

• A. Millipore Stericup
• B. Millipore Millex
• C. Sartorius Minisart
• D. Pall Acrodisc

Answer: (B)

For small-volume sterile filtration you want a syringe filter that mounts directly on a syringe and has minimal dead volume. Millex syringe filters from Millipore are designed for just that: they attach to a syringe, provide sterile filtration through a small-volume membrane (often 0.22 μm or 0.45 μm), and keep sample loss to a minimum. This makes them ideal when you’re working with only a few milliliters or less. The other options are more geared toward larger-volume workflows. Stericup is a bottle-top vacuum filtration system meant for bigger batches, so it introduces more dead volume and extra setup than you need for tiny samples. Sartorius Minisart and Pall Acrodisc are often used in bottle-top or cartridge formats intended for moderate to larger volumes, with configurations that aren’t as convenient for small-volume, direct syringe filtration.

For small-volume sterile filtration you want a syringe filter that mounts directly on a syringe and has minimal dead volume. Millex syringe filters from Millipore are designed for just that: they attach to a syringe, provide sterile filtration through a small-volume membrane (often 0.22 μm or 0.45 μm), and keep sample loss to a minimum. This makes them ideal when you’re working with only a few milliliters or less.

The other options are more geared toward larger-volume workflows. Stericup is a bottle-top vacuum filtration system meant for bigger batches, so it introduces more dead volume and extra setup than you need for tiny samples. Sartorius Minisart and Pall Acrodisc are often used in bottle-top or cartridge formats intended for moderate to larger volumes, with configurations that aren’t as convenient for small-volume, direct syringe filtration.