Which solvent is recommended to wipe the ointment slab before starting work?

Study for the Pharmaceutics II Exam 2 Concepts Test with flashcards and multiple choice questions. Each question has hints and explanations. Prepare effectively for your exam!

Multiple Choice

Which solvent is recommended to wipe the ointment slab before starting work?

Explanation:
Using a disinfectant with the right amount of water is key for effective cleaning of the ointment slab. A 70% solution of isopropanol is ideal because the water content facilitates protein denaturation and allows the alcohol to penetrate microbial cells more effectively, giving broad-spectrum antimicrobial action while remaining practical to use. Higher concentrations like 95% ethanol dry out and coagulate surface proteins too quickly, reducing penetration and kill. Water alone doesn’t disinfect, and methanol is toxic and not appropriate for this use. So, wiping with 70% isopropanol provides reliable surface disinfection for starting work.

Using a disinfectant with the right amount of water is key for effective cleaning of the ointment slab. A 70% solution of isopropanol is ideal because the water content facilitates protein denaturation and allows the alcohol to penetrate microbial cells more effectively, giving broad-spectrum antimicrobial action while remaining practical to use. Higher concentrations like 95% ethanol dry out and coagulate surface proteins too quickly, reducing penetration and kill. Water alone doesn’t disinfect, and methanol is toxic and not appropriate for this use. So, wiping with 70% isopropanol provides reliable surface disinfection for starting work.

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