What is incorporation?

What is incorporation?

• A. Components are mixed until uniformity
• B. Components are melted together
• C. Products are triturated with a liquid
• D. Base is dissolved in water

Answer: (A)

Incorporation is the mixing process used to blend a drug powder into a base until the distribution is uniform, typically in making semi-solid preparations like ointments. You soften or hold the base and slowly rub in or blend the powder until every part of the mixture has the same composition, often using methods like spatulation or geometric dilution to achieve even dispersion. The other terms describe different processes: melting components together is fusion, triturating with a liquid is levigation, and dissolving the base in water is dissolution. Therefore, mixing until uniformity best defines incorporation.

Incorporation is the mixing process used to blend a drug powder into a base until the distribution is uniform, typically in making semi-solid preparations like ointments. You soften or hold the base and slowly rub in or blend the powder until every part of the mixture has the same composition, often using methods like spatulation or geometric dilution to achieve even dispersion. The other terms describe different processes: melting components together is fusion, triturating with a liquid is levigation, and dissolving the base in water is dissolution. Therefore, mixing until uniformity best defines incorporation.